Factor X Deficiency
نویسندگان
چکیده
منابع مشابه
Hereditary coagulation factor X deficiency.
Stuart Prower factor (Factor X) deficiency is a rare hereditary autosomal recessive coagulation disorder. We have come across three cases in the course of last 20 years at our institute. These patients presented with prolonged bleeding after minor trauma, epistaxis, subcutaneous bluish black nodules and two of them presented with history of consanguinity in parents. Hematological findings in co...
متن کاملRecurrent Venous Thromboembolic Events in a Child with Severe Factor X Deficiency
Congenital factor X deficiency is a rare autosomal recessive bleeding disorder that presents with variable bleeding tendency and prolonged coagulation tests, prothrombin time, and partial thromboplastin time. Thromboembolic events have not been reported in patients with factor X deficiency yet. Herein, we report a patient with factor X deficiency who had recurrent venous thromboembolic events.
متن کاملFactor X deficiency in the neonatal period.
An infant with a severe deficiency of factor X presened in the neonatal period with uncontrollable bleeding from heel prick sites, spontaneous bruising, and haematoma. The deficiency was controlled by infusions of dried human factors II, IX, and X concentrate; the half-life of the infused factor X material is only 18 hours. Despite prophylactic weekly infusions of factor X concentrate, the chil...
متن کاملSteroid hormone-responsive secondary factor X deficiency.
disease and/or platelet activation, and may not participate directly in pathogenesis. We conclude that raised sP-selectin indicates a poor prognosis among patients with peripheral artery disease. The wide range of values means that this marker alone is unlikely to be of value in defining the risk of disease progression in any individual subject. However, it may be useful as part of a panel of m...
متن کاملA viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X
BACKGROUND Activated factor X (FXa) is a vitamin K-dependent serine protease that plays a pivotal role in blood coagulation by converting prothrombin to thrombin. There are no reports of humans with complete deficiency of FX, and knockout of murine F10 is embryonic or perinatal lethal. OBJECTIVE We sought to generate a viable mouse model of FX deficiency. METHODS We used a socket-targeting ...
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ژورنال
عنوان ژورنال: American Society for Clinical Laboratory Science
سال: 2010
ISSN: 0894-959X,1945-3574
DOI: 10.29074/ascls.23.3.131